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Table 2 Associations of anti-EBV antibodies with Odds ratio (OR) of gastric cancer risk

From: EBV antibody and gastric cancer risk: a population-based nested case-control study in southern China

 

Cases

Controls

Crude OR (95% CI)

Adjusted OR (95% CI)

Adjusted OR (95% CI)††

EBNA1-IgA

     

Negative

16 (88.9%)

422 (95.0%)

ref

ref

ref

Positive

2 (11.1%)

22 (5.0%)

2.59 (0.55,12.11)

2.59 (0.55,12.13)

2.59 (0.55,12.13)

EBNA1-IgA, rOD

  

1.98 (1.07,3.68)

1.99 (1.07,3.70)

1.99 (1.07,3.70)

VCA-IgA

     

Negative

16 (88.9%)

418 (94.1%)

ref

ref

ref

Positive

2 (11.1%)

26 (5.9%)

2.16 (0.47,9.82)

2.15 (0.47,9.95)

2.15 (0.47,9.95)

VCA-IgA, rOD

  

2.63 (1.33,5.20)

2.64 (1.33,5.23)

2.64 (1.33,5.23)

Serological risk (combination of VCA-IgA and EBNA-IgA)

     

Medium/Low

15 (83.3%)

431 (97.1%)

ref

ref

ref

High

3 (16.7%)

13 (2.9%)

6.49 (1.68,25.00)

6.53 (1.69,25.26)

6.53 (1.69,25.26)

  1. Abbreviations: EBV, Epstein-Barr virus; rOD, relative optical density; EBNA1: Epstein–Barr nuclear antigen 1; VCA: capsid antigen; IgA: Immunoglobulin A.
  2. OR was adjusted by age (numeric) at initial recruitment.
  3. ††OR was adjusted by age (numeric) at initial recruitment, sex, initial screening date, and residential town.