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Table 1 Baseline characteristics in gastric cancer cases and controls

From: EBV antibody and gastric cancer risk: a population-based nested case-control study in southern China

Characteristics

Gastric cancer

(N = 18)

Controls

(N = 444)

Total

(N = 462)

P

Sex, N (%)

   

1.000

Female

3 (16.7%)

90 (20.3%)

93 (20.1%)

 

Male

15 (83.3%)

354 (79.7%)

369 (79.9%)

 

Age at recruitment, N (%)

   

1.000

30 ~ 39

1 (5.6%)

30 (6.8%)

31 (6.7%)

 

40 ~ 49

2 (11.1%)

60 (13.5%)

62 (13.4%)

 

50 ~ 59

15 (83.3%)

354 (79.7%)

369 (79.9%)

 

Town, N (%)

   

0.655

Gangkou

2 (11.1%)

40 (9.0%)

42 (9.1%)

 

Minzhong

4 (22.2%)

53 (11.9%)

57 (12.3%)

 

Xiaolan

12 (66.7%)

351 (79.1%)

363 (78.6%)

 

Tumor histology

    

Adenocarcinoma

8 (44.4%)

   

Squamous cell carcinoma

2 (11.1%)

   

Unknown

8 (44.4%)

   

Tumor location

    

Cardia

1 (5.6%)

   

Non-cardia

6 (33.3%)

   

Unknown

11 (61.1%)

   

EBNA1-IgA, N (%)

   

0.399

Negative

16 (88.9%)

422 (95.0%)

438 (94.8%)

 

Positive

2 (11.1%)

22 (5.0%)

24 (5.2%)

 

EBNA-IgA, rOD

   

0.984

Median (Min, Max)

0.18 (0.02, 5.49)

0.19 (0.01, 2.57)

0.19 (0.01, 5.49)

 

VCA-IgA, N (%)

   

0.530

Negative

16 (88.9%)

418 (94.1%)

434 (93.9%)

 

Positive

2 (11.1%)

26 (5.9%)

28 (6.1%)

 

VCA-IgA, rOD

   

0.137

Median (Min, Max)

0.40 (0.14, 3.86)

0.30 (0.03, 3.05)

0.31 (0.03, 3.86)

 

Serological risk (combination of VCA-IgA and EBNA-IgA), N (%)

   

0.031

Medium/Low

15 (83.3%)

431 (97.1%)

446 (96.5%)

 

High

3 (16.7%)

13 (2.9%)

16 (3.5%)

 

VCA-IgA and EBNA-IgA, N (%)

   

0.422

Double negative

14 (77.8%)

398 (89.6%)

412 (89.2%)

 

Single positive

4 (22.2%)

44 (9.9%)

48 (10.4%)

 

Double positive

0 (0%)

2 (0.5%)

2 (0.4%)

 
  1. P values for the difference between case and control across numeric variables were derived by Kruskal-Wallis test while categorical variables by Fisher exact tests.
  2. Abbreviations: rOD, relative optical density.