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Fig. 5 | BMC Cancer

Fig. 5

From: Pharmacological inhibition of neuropeptide Y receptors Y1 and Y5 reduces hypoxic breast cancer migration, proliferation, and signaling

Fig. 5

NPYR antagonism increases expression of NPY1R and NPY5R, but reduces CAIX levels. Spheroids of MDA-MB-231 (A-C) and MCF7 (D-F) breast cancer cells were lysed and NPY1R (A and D), NPY5R (B and E), and CAIX (C and F) mRNA levels were measured by qRT-PCR. Data normalized to endogenous control genes RPLPO and RPL13A and made relative to normoxic monolayer. Bar graphs with error bars representing the SEM and * represent p < 0.05 using a one-way ANOVA and Tukey’s HSD post-hoc test

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BMC Cancer

ISSN: 1471-2407

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