Table 2 Clinical characteristics according to the first- and second-line treatments

Age, mean (SD)

61.27 (10.81)

59.0 (10.05)

64.05 (11.07)

 < 0.0001

60.81 (10.77)

62.61 (11.07)

61.16 (10.17)

0.0004

Age group

 < 0.0001

0.0106

  < 55

849 (26.2)

562 (31.5)

287 (19.7)

610 (27.8)

172 (22.3)

67 (24.3)

 55–59

529 (16.3)

338 (18.9)

191 (13.1)

357 (16.2)

121 (15.7)

51 (18.5)

 60–64

623 (19.2)

380 (21.3)

243 (16.6)

406 (18.5)

153 (19.8)

64 (23.2)

 65–69

459 (14.1)

222 (12.4)

237 (16.2)

316 (14.4)

106 (13.7)

37 (13.4)

  ≥ 70

787 (24.2)

285 (15.9)

502 (34.4)

509 (23.1)

221 (28.5)

57 (20.6)

Sex (%)

 < 0.0001

0.2816

 Male

2,534 (78.0)

1,444 (80.8)

1,090 (74.7)

1,700 (77.3)

610 (78.9)

224 (81.2)

 Female

713 (22.0)

343 (19.2)

370 (25.3)

498 (22.7)

163 (21.1)

52 (18.8)

Income level (%)

0.3507

0.3291

 0%–20% (lowest)

616 (19.0)

326 (18.2)

290 (19.9)

402 (18.3)

155 (20.0)

59 (21.3)

 20%–40%

468 (14.4)

264 (14.8)

204 (14.0)

318 (14.5)

114 (14.8)

36 (13.0)

 40%–60%

550 (16.9)

319 (17.9)

231 (15.8)

380 (17.3)

121 (15.7)

49 (17.8)

 60%–80%

684 (21.1)

381 (21.3)

303 (20.8)

451 (20.5)

182 (23.5)

51 (18.5)

 80%–100%

929 (28.6)

497 (27.8)

432 (29.5)

647 (29.4)

201 (26.0)

81 (29.4)

Residence (%)

0.1278

0.02

 Metropolitan

1,538 (47.4)

868 (48.6)

670 (45.9)

1,066 (48.5)

333 (43.1)

139 (50.4)

 Other region

1,709 (52.6)

919 (51.4)

790 (54.1)

1,132 (51.5)

440 (56.9)

137 (49.6)

CCI (%)

0.0071

0.7865

 0

1,056 (32.5)

621 (34.8)

435 (29.8)

730 (33.2)

237 (30.7)

89 (32.3)

 1–2

1,643 (50.6)

884 (49.4)

759 (52.0)

1,100 (50.1)

403 (52.1)

140 (50.7)

  ≥ 3

548 (16.9)

282 (15.8)

266 (18.2)

368 (16.7)

133 (17.2)

47 (17.0)

Department (%)

0.0016

 Urology

1,445 (44.5)

941 (52.6)

504 (34.5)

 < 0.0001

1,021 (46.5)

323 (41.8)

101 (36.6)

 Internal

1,753 (54.0)

825 (46.2)

928 (63.6)

1,145 (52.0)

434 (56.1)

174 (63.0)

 Others

49 (1.5)

21 (1.2)

28 (1.9)

32 (1.5)

16 (2.1)

1 (0.4)

Time from initial diagnosis to systemic treatment

0.8036

0.1589

  < 1 year

1,965 (60.5)

1,078 (60.3)

887 (60.7)

1,355 (61.6)

448 (58.0)

162 (58.7)

  ≥ 1 year

1,282 (39.5)

709 (39.7)

573 (39.3)

843 (38.4)

325 (42.0)

114 (41.3)