Table 3 Overall survival using Cox regression analysis

ICF vs. ICR

2.19 (1.00–4.82)

0.052

SEX(female vs. male)

1.33(0.74–2.38)

0.347

age (≦70 vs.>70 years)

0.98(0.50–1.92)

0.954

site(right vs. left)

0.42(0.17–1.02)

0.054

histology

 well differentiated vs. poorly or undifferentiated

0.47(0.15–1.51)

0.205

 moderately differentiated. vs. poorly or undifferentiated

0.45(0.16–1.31)

0.142

 RAS (wild vs. mutant)

0.55(0.29–1.03)

0.062

ECOG PS

 0 vs. 2

1.85(0.68–5.01)

0.225

 1 vs. 2

1.92(0.79–4.67)

0.149

 liver metastasis (-) vs. (+)

0.66(0.32–1.40)

0.280

 lung metastasis (-) vs. (+)

0.84(0.42–1.67)

0.610

 peritoneal metastasis (-) vs. (+)

0.47(0.17–1.32)

0.152

 Locally advanced tumour (-) vs. (+)

0.27(0.11–0.65)

<0.005^*