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Table 1 Multivariate logistic regression analysis of patients with inoperable or relapsed colon cancer

From: Correlation between overall survival and quality of life in colon cancer patients with chemotherapy

   

ICF

ICR

OR(95%CI)

P-value

Variable

n

(%)

n

(%)

n

(%)

   

sex

 female

36

(40.0)

32

(45.1)

4

(21.1)

0.44

(0.11–1.72)

0.238

 male

54

(60.0)

39

(54.9)

15

(78.9)

 

1.00(ref.)

 

age (years)

 ≦70

66

(73.3)

52

(73.2)

14

(73.7)

1.21

(0.28–5.33)

0.799

 >70

24

(26.7)

19

(26.8)

5

(26.3)

 

1.00(ref.)

 

ECOG PS

 0

28

(31.1)

17

(23.9)

11

(57.9)

9.94

(0.88–111.88)

0.063

 1

50

(55.6)

43

(60.6)

7

(36.8)

1.81

(0.18–18.42)

0.617

 2

12

(13.3)

11

(15.5)

1

(5.3)

 

1.00(ref.)

 

primary site

 right-sided

16

(17.8)

13

(18.3)

3

(15.8)

0.91

(0.13–6.50)

0.925

 left-sided

74

(82.2)

58

(81.7)

16

(84.2)

 

1.00(ref.)

 

histology

 well differentiated

25

(27.8)

20

(28.2)

5

(26.3)

1.58

(0.08–29.91)

0.761

 moderately differentiated

58

(64.4)

45

(63.4)

13

(68.4)

1.91

(0.13–27.47)

0.635

 poorly or undifferentiated

7

(7.8)

6

(8.5)

1

(5.3)

 

1.00(ref.)

 

RAS

 wild

43

(47.3)

30

(42.3)

13

(68.4)

3.16

(0.83–11.95)

0.092

 mutant

47

(51.6)

41

(57.7)

6

(31.6)

 

1.00(ref.)

 

metastasis

 liver

  (-)

31

(34.4)

21

(29.6)

10

(52.6)

4.47

(0.98–20.42)

0.053

  (+)

59

(65.6)

50

(70.4)

9

(47.4)

 

1.00(ref.)

 

 lung

  (-)

60

(66.7)

47

(66.2)

13

(68.4)

2.27

(0.46–11.23)

0.313

  (+)

30

(33.3)

24

(33.8)

6

(31.6)

 

1.00(ref.)

 

 peritoneum

  (-)

81

(90.0)

63

(88.7)

18

(94.7)

8.55

(0.52–139.56)

0.132

  (+)

9

(10.0)

8

(11.3)

1

(5.3)

 

1.00(ref.)

 

 locally advanced tumour

  (-)

77

(85.6)

60

(84.5)

17

(89.5)

3.99

(0.44–35.83)

0.217

  (+)

13

(14.4)

11

(15.5)

2

(10.5)

 

1.00(ref.)

 

  total

90

(100)

71

(100)

19

(100)

   
  1. CI Confidence interval, ECOG Eastern Cooperative Oncology Group, ICF Inoperable colon cancer at first onset, ICR Inoperable colon cancer at time of relapse, OR Odds ratio, PS Performance status, ref Reference