Table 5 Univariate and Multivariable analysis of factors potentially predictive of progress free interval

Age

1082

 <  = 60

601

Reference

 > 60

481

1.253 (0.904–1.738)

0.175

T stage

1079

T1

276

Reference

T2&T3&T4

803

1.886 (1.241–2.867)

0.003

1.609 (0.731–3.542)

0.237

N stage

1063

N0

514

Reference

N1&N2&N3

549

2.333 (1.621–3.357)

 < 0.001

1.771 (1.123–2.794)

0.014

M stage

922

M0

902

Reference

M1

20

8.315 (4.829–14.315)

 < 0.001

6.005 (3.115–11.573)

 < 0.001

Pathologic stage

1059

Stage I

180

Reference

Stage II&Stage III&Stage IV

879

2.268 (1.325–3.880)

0.003

0.867 (0.316–2.381)

0.782

ER status

1032

Negative

240

Reference

Positive

792

0.622 (0.436–0.887)

0.009

0.700 (0.394–1.244)

0.224

PR status

1029

Negative

342

Reference

Positive

687

0.558 (0.400–0.779)

 < 0.001

0.593 (0.343–1.025)

0.061

HER2 status

715

Negative

558

Reference

Positive

157

1.228 (0.712–2.119)

0.461

radiation_therapy

986

No

434

Reference

Yes

552

0.899 (0.631–1.281)

0.555

HSPB1

1082

Low

541

Reference

High

541

1.425 (1.137–1.750)

0.041