Table 4 Univariate and Multivariable analysis of factors potentially predictive of disease specific survival

Age

1062

 <  = 60

590

Reference

 > 60

472

1.445 (0.941–2.219)

0.093

1.280 (0.751–2.180)

0.364

T stage

1059

T1

274

Reference

T2&T3&T4

785

1.781 (1.033–3.071)

0.038

1.271 (0.525–3.080)

0.595

N stage

1044

N0

511

Reference

N1&N2&N3

533

3.797 (2.222–6.489)

 < 0.001

2.840 (1.451–5.559)

0.002

M stage

903

M0

884

Reference

M1

19

7.454 (3.988–13.931)

 < 0.001

6.663 (3.139–14.142)

 < 0.001

Pathologic stage

1041

Stage I

178

Reference

Stage II&Stage III&Stage IV

863

3.396 (1.478–7.803)

0.004

1.118 (0.300–4.165)

0.869

ER status

1013

Negative

232

Reference

Positive

781

0.559 (0.351–0.891)

0.015

0.435 (0.193–0.978)

0.044

PR status

1010

Negative

334

Reference

Positive

676

0.519 (0.334–0.807)

0.004

0.707 (0.321–1.555)

0.388

HER2 status

704

Negative

550

Reference

Positive

154

1.477 (0.740–2.948)

0.269

radiation_therapy

977

No

430

Reference

Yes

547

0.791 (0.483–1.295)

0.351

HSPB1

1062

Low

528

Reference

High

534

1.515 (1.239–1.837)

0.029