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Table 1 The relationship between the high and low expression of HSPB1 and different clinical indicators in patients with breast cancer

From: High HSPB1 expression predicts poor clinical outcomes and correlates with breast cancer metastasis

Characteristic

Low expression of HSPB1

High expression of HSPB1

p

n

541

542

 

Age, n (%)

  

0.133

  <  = 60

313 (28.9%)

288 (26.6%)

 

  > 60

228 (21.1%)

254 (23.5%)

 

T stage, n (%)

  

0.409

 T1

143 (13.2%)

134 (12.4%)

 

 T2

321 (29.7%)

308 (28.5%)

 

 T3

62 (5.7%)

77 (7.1%)

 

 T4

15 (1.4%)

20 (1.9%)

 

N stage, n (%)

  

0.003

 N0

282 (26.5%)

232 (21.8%)

 

 N1

175 (16.4%)

183 (17.2%)

 

 N2

52 (4.9%)

64 (6%)

 

 N3

26 (2.4%)

50 (4.7%)

 

M stage, n (%)

  

0.403

 M0

469 (50.9%)

433 (47%)

 

 M1

8 (0.9%)

12 (1.3%)

 

Pathologic stage, n (%)

  

0.032

 Stage I

91 (8.6%)

90 (8.5%)

 

 Stage II

327 (30.8%)

292 (27.5%)

 

 Stage III

102 (9.6%)

140 (13.2%)

 

 Stage IV

7 (0.7%)

11 (1%)

 

ER status, n (%)

  

 < 0.001

 Negative

187 (18.1%)

53 (5.1%)

 

 Positive

330 (31.9%)

463 (44.7%)

 

PR status, n (%)

  

 < 0.001

 Negative

225 (21.8%)

117 (11.3%)

 

 Positive

290 (28%)

398 (38.5%)

 

HER2 status, n (%)

  

0.337

 Negative

295 (40.6%)

263 (36.2%)

 

 Positive

78 (10.7%)

79 (10.9%)

 
  1. The p-values indicate significant differences between the low and the high expression of HSPB1 in clinical variables. For age, median (interquartile range), and other clinical variables, the Wilcoxon rank sum test and the chi-square test were used to calculate the p-values, respectively
  2. TMN stage was according to the seventh edition of the Guidelines for the American Journal of Critical Care. ER estrogen receptor, PR progesterone receptor, HER2 human epidermal growth factor receptor. Bold values indicate that p < 0.05