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Table 2 Summary of ongoing studies of RNSM

From: Mastectomy with Reconstruction Including Robotic Endoscopic Surgery (MARRES): a prospective cohort study of the Korea Robot-Endoscopy Minimal Access Breast Surgery Study Group (KoREa-BSG) and Korean Breast Cancer Study Group (KBCSG)

Identifier

Sample size

Randomization

Indication

Intervention

Postoperative outcomes

Oncologic outcomes

PRO

Country of origin

NCT04585074 (current study)

2000

No

Women with breast cancer

High-risk women

RNSM + ENSM

CNSM

Yes

Yes

Yes

South Korea

NCT04108117

300

No

Women with breast cancer

High-risk women

RNSM

CNSM

Yes

Yes

No

South Korea

NCT03440398

82

Yes

Women with breast cancer

High-risk women

RNSM

CNSM

Yes

Yes

Yes

Italy

NCT03892980

145

No

High-risk women

RNSM

Yes

No

No

United States

NCT04537312

20

No

Women with breast cancer

High-risk women

RNSM

Yes

No

Yes

United States

NCT04457167

480

No

Women with breast cancer

High-risk women

RNSM

CNSM

Yes

No

No

France

NCT04151368

30

No

Women with breast cancer

High-risk women

RNSM

Yes

Yes

Yes

Canada

NCT04037852

180

No

Women with breast cancer

RNSM

CNSM or ENSM

Yes

Yes

Yes

Taiwan

  1. CNSM conventional nipple-sparing mastectomy, ENSM endoscopic nipple-sparing mastectomy, PRO Patient-reported outcome, RNSM robot-assisted nipple-sparing mastectomy