Fig. 7
From: CYD0281, a Bcl-2 BH4 domain antagonist, inhibits tumor angiogenesis and breast cancer tumor growth
CYD0281 suppresses tumor growth and angiogenesis of 4T1 breast cancer cells subcutaneous implant tumor model. A Representative macroscopic images of tumors. Quantification of tumor volume (B), and tumor weight (C). D CD31 immunohistochemistry images of tumor tissue sections. E Quantification of microvessel density (MVD). Significant effect between the groups (B), and compared to DMSO group (C and E): *P < 0.05 and **P < 0.01. Scale bars: 100 μm