Fig. 3

Case-study: Utility of ABPEPserver. A A scatter plot from ABPEPserver (W > F Substitutants module) for UCEC (Uterine Cancer), depicting total occurrences in tumour tissue samples on X-axis and Total occurrences in adj. normal tissue samples on Y-axis. Identification of two peptides that are selected to be highly tumour-specifically expressed. The database used for this scatter plot is the fully substitutant database (database 1). B, C Tables displaying peptide combinations for the selected peptides in (A) that have HLA-binding ability to one or more HLA super alleles. Rank is displayed as inverse rank from NETMHC ²³analysis where peptides rank < 1 are identified as strong binders and rank > 1 & rank < 2 are identified as weak binders