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Table 3 Histological summary of mice with exposed materials and the days of tumor development

From: Matrigel-based organoid culture of malignant mesothelioma reproduces cisplatin sensitivity through CTR1

Organoid ID

Material

mouse genotype

Mesothelioma incidence

Histology

Days

Subtype

MSLN

WT1

m5

Crocidolite

P53 +/-

211

Biphasic

 + 

 + 

m12

Crocidolite

P53 +/- 

156

Biphasic

-

-

m28

Crocidolite

P53 +/- 

221

Sarcomatoid

 + 

 + 

m54

Crocidolite

P53 +/- 

173

Sarcomatoid

 + 

-

m60

Crocidolite

P53 +/-

194

Biphasic

-

-

m67

Crocidolite

P53 + / + 

139

ND(Ascites)

ND(Ascites)

ND(Ascites)

m107

NT50

P53 +/- 

174

Sarcomatoid

 + 

 + 

  1. NT Carbon nanotube, ND Not determined. Refer to text for details