Fig. 4From: Matrigel-based organoid culture of malignant mesothelioma reproduces cisplatin sensitivity through CTR1Transcriptome profiling of malignant mesothelioma (MM)-derived organoids and 2D-culture. a Comparison of transcriptional profiles of mesothelioma cells obtained from traditional 2D culture (2D, gray bar) and Matrigel-based 3D culture (3D, green bar). Red and blue colors indicate upregulation and downregulation, respectively. b, c Top gene ontology (GO) using Enrichr molecular function and PPI Hub proteins terms related to differentially expressed genes between 2D and 3D cultures of mouse MMsBack to article page