Table 5 Outcome of the low-risk CBF AML study population by number of treatment courses received
Four courses (n = 218) | Five courses (n = 184) | P value | |||
|---|---|---|---|---|---|
% | 95%CI | % | 95%CI | ||
CBF (n = 402) | |||||
10-years CIR | 30.9 | 24.7–37.2 | 27.4 | 21.2–34.4 | 0.42 |
10-years OS | 82.8 | 75.1–91.2 | 85.4 | 80.4–90.8 | 0.91 |
inv(16) (n = 164), No. of patients | 83 | 81 | |||
10-years CIR | 33.9 | 23.7–44.5 | 36.1 | 25.7–46.6 | 0.67 |
10-years OS | 92.2 | 86.5–98.4 | 88.4 | 81.5–95.8 | 0.52 |
t(8;21) (n = 238), No. of patients | 135 | 103 | |||
10-years CIR | 29.3 | 21.7–37.3 | 19.8 | 12.6–28.1 | 0.06 |
10-years OS | 77 | 65.8–90.2 | 83 | 75.9–90.7 | 0.73 |