Fig. 7

Vasculature in tumors formed by SCCVII/SF-GFP (SCC), D2, and D3 cells. (A) CD31 IHC: Top panel: bright field view. Lower panel: computer-generated segmented CD31 + Signals. Representative data of biological replicates are shown. (B). Quantified results of micro-vessel density (MVD) and micro-vessel wall thickness (MVWT). Each dot on the scatter plot represents the averaged data value generated from one mouse. Since the D3 hybrid cells often failed to form tumors, the number of animals allowed for analysis was smaller than those used for the D2 and control cells. F: female, M: male. *p ≤ 0.05, **p ≤ 0.01