Fig. 3From: Decision-analytic evaluation of the comparative effectiveness and cost-effectiveness of strategies to prevent breast and ovarian cancer in German women with BRCA-1/2 mutationsCost-effectiveness plane of different preventive strategies:(A) discounted total life-time costs (in €) versus effectiveness expressed in discounted total life years (LYs) and (B) discounted total life-time costs (in €) versus discounted total quality-adjusted life years (QALYs). The respective stepwise ICER (in €/LY) and ICUR (in €/QALY) on the efficiency frontier (blue line) are shown in boxes. Reference strategy: PBM at age 30 and PBSO at age 40 (S12)PBM: Prophylactic bilateral mastectomy; PBSO: Prophylactic bilateral salpingo-oophorectomy; y: years of ageBack to article page