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Fig. 1 | BMC Cancer

Fig. 1

From: Decision-analytic evaluation of the comparative effectiveness and cost-effectiveness of strategies to prevent breast and ovarian cancer in German women with BRCA-1/2 mutations

Fig. 1

Illustration of the decision-analytic model. Health states representing the natural history of breast and ovarian cancer represented in the Markov model are shown as bubbles: No breast and ovarian cancer (well), undetected invasive breast cancer stage I to stage IV, diagnosed invasive breast cancer stage I to stage IV (pT1- pT4), breast cancer survivors 10 years after initial breast cancer diagnosis and treatment (breast cancer survivor), death from breast cancer (breast cancer death), undetected invasive ovarian cancer stage I to stage IV, diagnosed invasive ovarian cancer stage I to stage IV (FIGO states I–IV), ovarian cancer survivors 10 years after ovarian cancer diagnosis and treatment (ovarian cancer survivor), death from ovarian cancer (ovarian cancer death), and death from other causes (death other causes). Progression from one health state to the other is indicated with solid arrows and remaining in the same health state with curved arrows

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