Number of patients (%) | Time to treatment discontinuation (months), mean (SD) | |||||
---|---|---|---|---|---|---|
Total | De novo patients | Relapsed/progressed patients | Total | De novo patients | Relapsed/progressed patients | |
First-line regimen | 14,505 (100.0) | 12,811 (100.0) | 1,694 (100.0) | 2.9 (2.7) | 2.8 (2.5) | 3.0 (4.0) |
Paclitaxel + platinum | 4,758 (32.8) | 4,387 (34.2) | 371 (21.9) | 2.8 (2.9) | 2.8 (2.9) | 2.5 (2.8) |
Pemetrexed + platinum | 4,063 (28.0) | 3,763 (29.4) | 300 (17.7) | 2.7 (1.3) | 2.7 (1.3) | 2.6 (1.1) |
Gemcitabine + platinum | 4,042 (27.9) | 3,631 (28.3) | 411 (24.3) | 2.9 (2.7) | 2.9 (2.4) | 3.1 (4.3) |
Gemcitabine | 430 (3.0) | 337 (2.6) | 93 (5.5) | 2.8 (4.8) | 2.8 (5.2) | 2.6 (3.0) |
Docetaxel + platinum | 329 (2.3) | 295 (2.3) | 34 (2.0) | 3.1 (2.1) | 3.2 (2.1) | 2.2 (1.7) |
Others | 883 (6.1) | 398 (3.1) | 485 (28.6) | 3.6 (4.9) | 3.4 (4.1) | 3.7 (5.4) |
Second-line regimen | 5.973 (100.0) | 5,314 (100.0) | 659 (100.0) | 3.8 (4.9) | 3.7 (4.9) | 3.8 (5.1) |
Docetaxel | 1,127 (18.9) | 996 (18.7) | 131 (19.9) | 2.4 (2.3) | 2.4 (2.3) | 2.3 (1.9) |
Gemcitabine + platinum | 946 (15.8) | 860 (16.2) | 86 (13.1) | 2.6 (2.3) | 2.6 (2.4) | 2.5 (1.9) |
Pembrolizumab | 822 (13.8) | 765 (14.4) | 57 (8.7) | 7.0 (7.6) | 6.9 (7.5) | 8.7 (8.6) |
Nivolumab | 688 (11.5) | 617 (11.6) | 71 (10.8) | 6.0 (7.0) | 5.9 (6.9) | 6.6 (8.1) |
Paclitaxel + platinum | 404 (6.8) | 373 (7.0) | 31 (4.7) | 2.7 (3.9) | 2.7 (3.8) | 3.3 (5.3) |
Others | 1,986 (33.3) | 1,703 (32.1) | 283 (42.9) | 3.2 (3.9) | 3.1 (3.8) | 3.3 (3.9) |