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Table 1 Prognostic significance of 5-year DFS in current staging category and modified staging category

From: Prognostic value of tumor necrosis based on the evaluation of frequency in invasive breast cancer

Variables

Training Set

Validation Set

HR (95%CI)

P Value

HR (95%CI)

P Value

Current staging category

 I

Reference

 

Reference

 

 II

1.827 (1.024–3.258)

0.041

1.784 (0.939–3.389)

0.077

 III

5.372 (2.974–9.704)

< 0.0001

4.504 (2.372–8.552)

< 0.0001

Modified staging category

 I-n (I with no high-risk TN)

Reference

   

 II-n (I with high-risk TN + II with no high-risk TN)

1.973 (1.014–3.839)

0.045

1.928 (0.945–3.934)

0.071

 III-n (II with high-risk TN + III)

6.011 (3.136–11.523)

< 0.0001

4.953 (2.468–9.940)

< 0.0001