From: Biological evaluation of novel gemcitabine analog in patient-derived xenograft models of pancreatic cancer
IC50 μM
(PPCL-46)
(PPCL-68)
(PPCL-135)
(PPCL-192)
GemHCl
56 ± 1.8
57 ± 2.4
56 ± 1.5
57 ± 1.5
4NSG-SLN
12 ± 2.1
22 ± 2.6
11 ± 1.3
9 ± 1.1