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Table 2 Logistic regression models examining index measures at month-6 as mediators of intervention effect on alter cervical cancer (CC) screening

From: Mediators and moderators of the effect of the game changers for cervical cancer prevention intervention on cervical cancer screening among previously unscreened social network members in Uganda

 

CC Knowledge

Sharing CC screening experience

CC prevention advocacy

Mean CC screening advocacy across all alters

Without mediator

With mediator

Without mediator

With mediator

Without mediator

With mediator

Without mediator

With mediator

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

OR (95% CI)

Intervention

1.75

(1.60, 1.91)

3.49 (0.21, 57.29)

1.15

(1.06, 1.24)

3.72

(0.13, 109.20)

1.47

(1.37, 1.59)

7.78

(0.71, 85.32)

1.10

(1.07, 1.12)

3.58

(0.99, 12.90)

Direct effect

 

67.15 (0.21, 21868.35)

 

7.50

(1.50, 37.42)

 

70.89

(4.54, 1106.88)

 

6.95

(1.72, 28.04)

CC knowledge (bsln)

1.01

(1.00, 1.02)

1.07 (0.96, 1.19)

--

--

--

--

--

--

CC knowledge (M6)

--

1.06 (0.63, 1.79)

--

--

--

--

--

--

Sharing CC screening experience (bsln)

--

--

1.12

(1.01, 1.25)

0.62 (0.30, 1.29)

--

--

--

--

Sharing CC screening experience (M6)

--

--

--

1.84 (0.15, 23.06)

--

--

--

--

CC prevention advocacy (bsln)

--

--

--

--

1.07

(1.04, 1.10)

1.09 (0.87, 1.37)

--

--

CC prevention advocacy (M6)

--

--

--

--

--

0.70 (0.26, 1.84)

--

--

Mean CC screening advocacy (bsln)

--

--

--

--

--

--

0.98

(0.92, 1.04)

1.02

(0.47, 2.18)

Mean CC screening advocacy (M6)

--

--

--

--

--

--

--

4.19

(1.58, 11.15)

Indirect effect

 

0.14 (0.00, 41.10)

 

1.48 (0.94, 2.33)

 

0.13 (0.01, 1.84)

 

1.53

(0.80, 2.92)

  1. A two-step approach was used to test each potential mediator separately. In step one (“without mediator column”), the dependent variable was alter uptake of CC screening by month 6, while independent variables consisted of an indicator of study arm and the baseline measure of the mediator. In step two (“with mediator column”), the month 6 measure of the mediator was added to the model. Covariates included in each model consisted of age < 35 years, any secondary education, and presence of a main sex partner
  2. OR = odds ratio; CI = confidence interval; bsln = baseline; M6 = month-6 follow-up visit