Fig. 1

Genetic variation of KDM genes in gastric cancer. A The workflow being used in our work. B Using KDMs to discriminate tumors from normal tissue by principal component analysis (PCA). C Genetic alterations of 24 KDMs in GC tumors was demonstrated in oncoplot. Each column was each GC patient’s mutation data and mutation frequency of each gene was displayed on the right side. D Locations of CNV alterations in KDMs on 13 chromosomes. E 10 CRGs’ CNV diversity in GC tissues using TCGA-STAD data. F Boxplot shows the expression difference between normal and GC tissues in TCGA-STAD cohort. Statistical difference is identified by Wilcox test, * indicating P value < 0.05; ** indicating P value < 0.01; *** indicating P value < 0.001