Fig.1

A Incidence of SETD2 deleterious mutations in pan-cancer. Red, green, and blue bars represent the frequency of SETD2 nonsynonymous mutations in pan-cancer in the Geneplus cohort. (Nonsynonymous mutations include frameshift indels, inframe indels, missense mutations, nonsense mutations, nonstop mutations, and translation start site mutations.) B The domains and the corresponding mutation sites of SETD2 mutations. Domains and the corresponding mutation sites of the SETD2 gene identified in the Geneplus cohort. Green, red, blue, brown, orange, and purple dots represent Missense_Mutation, Nonsense_Mutation, Frame_Shift_Del, In_Frame_Del, Splice_Site, and Frame_Shift_Ins, respectively. C Proportion of SETD2 mutation forms by cohort and cancer type