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Fig. 8 | BMC Cancer

Fig. 8

From: A comprehensive analysis of different types of databases reveals that CDH1 mRNA and E-cadherin protein are not downregulated in most carcinoma tissues and carcinoma cell lines

Fig. 8

Positive correlation between CDH1 mRNA levels and E-cad protein levels in carcinoma cell lines. A, The CDH1 mRNA levels and E-cad protein levels in carcinoma cell lines are positively correlated (R = 0.845). CDH1 mRNA and E-cad protein data from tumor cell lines derived from the endometrium (n = 14), head/neck (n = 10), pancreas (n = 19), ovary (n = 17), lung (n = 77), liver (14), kidney (n = 12), colon (n = 29), and breast (n = 30) were used in the plot. CDH1 mRNA and E-cad data were obtained from Expression 22Q1 Public and Proteomics datasets in the DepMap portal (https://depmap.org/portal/). B and C, OS and DFS of breast, colon, lung, pancreatic, ovarian, and endometrial carcinoma patients who carry tumors with upregulated CDH1 mRNA (High = 1,298; Low = 1,298) based on CDH1 mRNA expression. C and D, OS and DFS of kidney carcinoma patients who carry tumors with downregulated CDH1 (High = 258; Low = 258) based on CDH1 mRNA expression. F and G, OS and DFS of liver and head/neck carcinoma patients who carry tumors with the unchanged expression of CDH1 (High = 441; Low = 441) based on CDH1 mRNA expression

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BMC Cancer

ISSN: 1471-2407

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