Fig. 8

Effect of miR-188 on xenograft hepatocellular carcinoma (HCC) tumorigenesis. LM3 cells stably expressing miR-188 or the control were subcutaneously administered to mice (n = 6 in each group). On day 28 post-inoculation, the animals were sacrificed, and tumors were weighed. A miR-188 and FOXN2 expression levels were measured in each group using qPCR. B Tumor growth curve at 27 days post-inoculation. C Tumor weights on day 28 post-inoculation. D Images of tumors from nude mice 28 days post-inoculation. * P < 0.05, ** P < 0.01, *** P < 0.001