Fig. 6

Stable upregulation of FOXN2 on growth of HLF and LM3 cells. A HLF and LM3 cells stably expressing FOXN2 were treated with doxycycline (Dox, 50 ng/ml). After 166 h, the cells were harvested and subjected to RT-qPCR. The expression level of FOXN2 mRNA was determined by PCR. B HLF and LM3 cells with miR-188 mimic transfection was treated with doxycycline (Dox, 50 ng/ml). After 166 h, the cells were harvested and subjected to qPCR. The expression level of FOXN2 mRNA was determined by qPCR. C The CCK-8 assay was used to determine cell viability at 72 h post-transfection. D The cell growth rate was determined by colony formation assay. ** P < 0.01