Fig. 2

Role of miR-188 on growth and colony formation of hepatocellular carcinoma (HCC) cell lines. HepG2, Hep3B, LM3, and HLF cells were transfected with the miR-188 mimic/inhibitor or NC mimic/inhibitor for 72 h. A At 72 h post transfection, qPCR was carried out to detect miR-188 levels in HLF, LM3, Hep3B, and HepG2cells. B HepG2, Hep3B, LM3, and HLF cells were transfected with miR-188 mimic/inhibitor or NC mimic/inhibitor for 72 h. CCK-8 assays were used to determine cell viability at 72 h post-transfection. C Colony formation assays were used to determine the growth rates of these four HCC cell lines. * P < 0.05, ** P < 0.01