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Table 3 Observed fraction of eradicated tumors observed in each treatment group

From: Model-based assessment of combination therapies – ranking of radiosensitizing agents in oncology

Test Compound

Dose [mg/kg]

Observed fraction of eradicated tumors

Study 1

\(R{s}_{1}\)

100

1/9

\(R{s}_{2}\)

25

9/9

\(R{s}_{2}\)

100

8/9

\(R{s}_{3}\)

20

6/9

Study 2

\(R{s}_{1}\)

10

0/10

\(R{s}_{1}\)

50

1/10

\(R{s}_{1}\)

200

3/9a

Study 3

\(R{s}_{1}\)

25

8/10

\(R{s}_{1}\)

50

8/9a

\(R{s}_{1}\)

100

10/10

  1. aOne early dropout not included