From: Model-based assessment of combination therapies – ranking of radiosensitizing agents in oncology
Test Compound | Dose [mg/kg] | Observed fraction of eradicated tumors |
---|---|---|
Study 1 | ||
\(R{s}_{1}\) | 100 | 1/9 |
\(R{s}_{2}\) | 25 | 9/9 |
\(R{s}_{2}\) | 100 | 8/9 |
\(R{s}_{3}\) | 20 | 6/9 |
Study 2 | ||
\(R{s}_{1}\) | 10 | 0/10 |
\(R{s}_{1}\) | 50 | 1/10 |
\(R{s}_{1}\) | 200 | 3/9a |
Study 3 | ||
\(R{s}_{1}\) | 25 | 8/10 |
\(R{s}_{1}\) | 50 | 8/9a |
\(R{s}_{1}\) | 100 | 10/10 |