Fig. 4

HSPB1 phosphosites contributed to GBM survival. (A) Forest plot showing the result of univariate Cox-regression analysis for correlation between the phosphosites of five risk ferroptosis regulators and the overall survival. (B) Kaplan-Meier curves of GBM samples stratified by the phosphorylation abundances of HSPB1 with log-rank test P-value provided, respectively. (C) Violin plots showing the differences in phosphorylation abundances of HSPB1 between high-risk and low-risk groups. P-values were calculated by Mann–Whitney U test as *P ≤ 0.05; **P ≤ 0.01; ****P ≤ 0.0001. (D) ROC curve showing the performances of HSPB1 phosphosites for distinguishing GBM risk groups. (E) Bubble plot showing the correlations between HSPB1 phosphosites and kinases. (F) Co-expressed network of HSPB1. (G) Function enrichment of HSPB1 co-expressed proteins using Metascape