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Fig. 2 | BMC Cancer

Fig. 2

From: Proteogenomic characterization of ferroptosis regulators reveals therapeutic potential in glioblastoma

Fig. 2

Proteogenomic regulation of ferroptosis regulators. (A) Barplot showing the SNV class in CPTAC-GBM and TCGA-GBM cohorts, respectively. (B) Top 10 mutated genes in CPTAC-GBM and TCGA-GBM cohorts, respectively. (C) Oncoplots showing the five common mutated genes in both CPTAC-GBM and TCGA-GBM cohorts. (D) Heatmap showing the differential expression of mRNA, protein, and phosphoprotein between mutated and wild samples. (E) Heatmap showing the effect of EGFR, IDH1, PIK3CA, RB1, and TP53 mutations on protein abundances of ferroptosis regulators

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