Fig. 2

ZDHHC15 mRNA and protein levels in glioma tissues in our cohort. (A-C) Relative mRNA level of ZDHHC15 in grades 2–4 glioma (A), Non-GBM and GBM (B), IDH mutant and wild-type glioma (C), Student’s t-test. (D-E) Association of ZDHHC15 protein expression with tumor grades. (F-G) Association of ZDHHC15 protein expression with glioma IDH status. -, no expression (percentage of positive tumor cells ≤ 5% and staining intensity was negative); +, weak expression (percentage of positive tumor cells 6–25% and staining intensity was weak); ++, median expression (percentage of positive tumor cells 26–75% and staining intensity was intermediate); +++ indicates high expression (percentage of positive tumor cells >75% and staining intensity was high). Pearson chi-square test, ^*P < 0.05, ^**P < 0.01. Scale bars, 100 μm