Skip to main content

Table 3 Univariable and multivariable cox regression analyses of UTIs in the study population

From: Urinary tract infection after radiation therapy or radical prostatectomy on the prognosis of patients with prostate cancer: a population-based study

Variables

Number of patients at risk

No. (%)

Person-years

Incidence rate (per 1,000 person-years)

Univariable

Multivariable

HR (95% CI)

p-values

HR (95% CI)

p-values

Treatment

 - Radiation

5,094

930 (18.3)

23546.5

39.5

1 (reference)

 

1 (reference)

 

 - \(<\) 20 m Robot-assisted

11,053

1,021 (9.2)

17043.2

59.9

1.27 (1.13 – 1.44)

< 0.001

1.26 (1.11 – 1.43)

< 0.001

 - \(\ge\) 20 m Robot-assisted

9,666

1,124 (11.6)

34597.2

32.5

0.91 (0.69 – 1.20)

0.504

0.92 (0.70 – 1.23)

0.573

 - \(<\) 20 m Open/laparoscopic

12,740

1,439 (11.3)

19431.0

74.1

1.57 (1.40 – 1.76)

 < 0.001

1.63 (1.44–1.83)

< 0.001

 - \(\ge\) 20 m Open/laparoscopic

11,091

1,804 (16.3)

50555.4

35.7

1.01 (0.78 – 1.31)

0.940

1.02 (0.78 – 1.34)

0.887

Age Group at PC diagnosis

 - \(<\) 75 y

24,363

5,309 (21.8)

126339.1

42.0

1 (reference)

 

1 (reference)

 

 - \(\ge\) 75 y

4,524

1,009 (22.3)

18847.1

53.5

1.22 (1.14 – 1.30)

< 0.001

1.19 (1.11 – 1.28)

< 0.001

CCI score

 - 0–1

6,718

1,201 (17.9)

38550.1

31.2

1 (reference)

 

1 (reference)

 

 - 2–3

10,089

2,082 (20.6)

52526.6

39.6

1.25 (1.17–1.34)

< 0.001

1.20 (1.12–1.29)

< 0.001

 - ≥ 4

12,080

3,035 (25.1)

54109.4

56.1

1.72 (1.61–1.84)

< 0.001

1.53 (1.42–1.64)

< 0.001

Diabetes

 - NO

18,307

3,666 (20.0)

92335.5

39.7

1 (reference)

 

1 (reference)

 

 - YES

10,580

2,652 (25.1)

52850.6

50.2

1.26 (1.20–1.33)

< 0.001

1.10 (1.04–1.16)

0.001

Renal disease

 - NO

27,270

5,826 (21.4)

137236.8

42.5

1 (reference)

 

1 (reference)

 

 - YES

1,617

492 (30.4)

7949.4

61.9

1.45 (1.32–1.59)

< 0.001

1.30 (1.19–1.43)

< 0.001

Hypertension

 - NO

23,522

4,975 (21.2)

117097.2

42.5

1 (reference)

 

1 (reference)

 

 - YES

5,365

1,343 (25.0)

28089.0

47.8

1.14 (1.07–1.21)

< 0.001

1.01 (0.95–1.08)

0.707

ADT

 - NO

21,806

4,847 (22.2)

113275.4

42.8

1 (reference)

 

1 (reference)

 

 - YES

7,081

1,471 (20.8)

31910.8

46.1

1.05 (0.99–1.11)

0.134

1.13 (1.06–1.20)

< 0.001

Anticholinergic drugs

 - NO

17,759

3,489 (19.7)

92257.5

37.8

1 (reference)

 

1 (reference)

 

 - YES

11,128

2,829 (25.4)

52928.7

53.4

1.39 (1.32–1.46)

< 0.001

1.34 (1.27–1.41)

< 0.001

  1. The model was adjusted for age at PC diagnosis, period of PC diagnosis, CCI score, diabetes, renal disease, hypertension, anticholinergic drug, and androgen deprivation therapy
  2. Abbreviations: OS overall survival, PC prostate cancer, UTI urinary tract infection, ADT androgen deprivation therapy, CCI Charlson Comorbidity Index
Back to article page

BMC Cancer

ISSN: 1471-2407

Contact us