Skip to main content

Table 2 IC50 of SNRPD1 or SNRPE silenced cells in response to doxorubicin treatment in triple negative breast cancer cells. ‘Gene’ shows the gene targeted by siRNA. ‘IC50’ and ‘SE’ each lists the estimate and standard error of the IC50 values. The p-value shows the significance of the difference between siRNA transfected and control cells in each cell line

From: SNRPD1 conveys prognostic value on breast cancer survival and is required for anthracycline sensitivity

Cell line

Gene

Type

IC50

SE

p

MDAMB231

SNRPD1

siRNA

676.83

23.09

5.50E-6

 

SNRPD1

control

177.82

21.98

 

HCC1937

SNRPD1

siRNA

239.49

22.17

4.35E-10

 

SNRPD1

control

93.81

7.29

 

MDAMB231

SNRPE

siRNA

143.82

20.8

0.7861

 

SNRPE

control

139.84

21.23

 

HCC1937

SNRPE

siRNA

208.39

21.03

0.8199

 

SNRPE

control

211.59

19.16