Fig. 4

Effect on cell viability and migration by modulating SNRPD1 or SNRPE in MCF7 and MDAMB231 cells. The effect on cell viability after knocking down (A) SNRPD1 and (B) SNRPE at 48 hours after transfection. The effect on cell migration after knocking down (C) SNRPD1, (D) SNRPE for 12 hours (after wounding was made), and over-expressing (E) SNRPD1, (F) SNRPE for 12 hours (after wounding was made). Student’s t-test p values were computed for MDAMB231 and MCF7 as compared with each control. ‘-KD’ is short for ‘knockdown’, ‘-OE’ symbolizes ‘over-expression’, and ‘-C’ represents ‘control’. ‘GenePharma Silencer Select Negative Control’ was used as the negative control for gene silencing