Table 4 Association of Osteopontin variants with overall survival by cancer patients in TSVdb. For each cancer in TSVdb, the Osteopontin splice variant levels were analyzed for the comparison of 5-year survival versus non-survival. The Table lists only the significant p-values (< 0.05) for one-tailed t-tests assuming equal variance (no entry means no significant differences were found). The second column from the left (n) indicates the number of available data sets. OPN-a, OPN-b, OPN-c, OPN-4, and OPN-5 are the splice variants captured

adrenocortical carcinoma

49

pheochromocytoma/paraganglioma

117

kidney chromophobe

161

renal clear cell carcinoma

524

0.01

renal papillary cell carcinoma

254

0.0113

bladder urothelial carcinoma

311

prostate adenocarcinoma

434

testicular germ cell tumor

128

ovarian serous cystadenocarcinoma

298

cervical cancers

233

0.0251

0.0061

0.0152

endometrial carcinoma

165

uterine carcinosarcoma

21

breast adenocarcinoma

993

esophageal carcinoma

136

stomach adenocarcinoma

318

colon adenocarcinoma

268

0.0322

rectum adenocarcinoma

89

cholangiocarcinoma

20

0.0063

0.0057

hepatocellular carcinoma

314

0.0153

0.0421

pancreatic adenocarcinoma

148

lung adenocarcinoma

430

0.0463

lung squamous cell carcinoma

421

0.0338

0.0398

mesothelioma

33

thyroid carcinoma

465

thymoma

113

diffuse large B-cell lymphoma

146

acute myeloid leukemia

0

head and neck cancer

440

glioblastoma

150

brain lower grade glioma

471

2E-07

3E-07

3E-07

cutaneous melanoma

87

0.0041

0.0112

0.0017

uveal melanoma

166

sarcoma

202