Fig. 2

Tumor-forming ability of PCa cells in prostate and the expression level of KLF7 in tumor tissues under obesity. A-B The BALB/c nude mice were fed with 60% high fat diets, the weight (A) and Lee’s index (B) were detected. C The tumor-forming ability of PC3 cells in the prostates of the two groups of mice was observed by small animal imaging. D-F Immunohistochemistry was used to detect the expression levels of KLF7 (D), p21 (E) and Ki67 (F) in tumer tissues from ND group(up) and HFD group(down) (100 × , 200 ×). G-I Immunohistochemical score of KLF7 (G), p21 (H) and Ki67 (I). J Western Blot was used to detect the protein expression level of IL-6 in tumor tissues from ND group and HFD group. Non-parametric rank sum test, *P < 0.05, **P < 0.01, ***P < 0.001 the difference was statistically significant