Table 5 Results of stepwise Cox regression analysis on breast cancer-specific survival and overall survival in HR-positive breast cancer patients
From: High leukocyte mitochondrial DNA copy number contributes to poor prognosis in breast cancer patients
Factor (in order of entry) | HR (95%CI) | P (in final modal) |
|---|---|---|
5-Year Breast Cancer-Specific Survival | Â | Â |
1. Nodal status(positive vs. negative) | 4.148 (2.186–7.783) | <0.001 |
2. Grade(III vs. I + II) | 1.859 (1.138–3.035) | 0.013 |
3. mtDNAcn(Quintile 2–5 vs. Quintile 1) | 2.420 (1.204–4.863) | 0.013 |
5-Year Overall Survival | Â | Â |
1. Nodal status(positive vs. negative) | 3.454 (1.900-6.279) | <0.001 |
2. mtDNAcn(Quintile 2–5 vs. Quintile 1) | 2.464 (1.227–4.948) | 0.011 |
3. Grade(III vs. I + II) | 1.705 (1.046–2.777) | 0.032 |
4. HER2(positive vs. negative) | 1.537 (0.959–2.463) | 0.073 |