Fig. 6

Infiltration of CD36⁺CD8⁺ T cells in the TME is accompanied by Tregs and M2. A, B. Representative pictures of immune cell infiltration in CD36⁺ T cells high or low group. C. Comparison of various immune cell types between high and low CD36⁺CD8⁺ T cells proportion subgroups. D. Heat map displays scaled expression of various immune cell types between high and low CD36⁺CD8⁺ T cells proportion subgroups. E. Linear regression showed a positive correlation between CD36⁺CD8⁺ T cells with Tregs or M2. ns: no significance, *p < 0.05 and **p < 0.01 by Mann–Whitney U test; CD8 = CD8⁺ T cells; CD4 = CD4⁺ T cells; Th1 = Type 1 T helper cells; Th2 = Type 2 T helper cells; Treg = regulatory T cells; NK = nature killer cells; DC = dendritic cells; M1 = M1 macrophages; M2 = M2 macrophages