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Table 3 Sensitivity, specificity, positive predictive values, and negative predictive values of various PET-CT reporting methods

From: PET-CT detection of local residual laryngeal carcinoma after definitive (chemo)radiotherapy

 

Sensitivity, % (95%CI)

Specificity, % (95%CI)

PPV, % (95%CI)

NPV, % (95%CI)

Accuracy, %

Sensitive interpretation

100.0 (66.7–100.0)

75.0 (62.8–87.3)

36.0 (4.7–67.4)

100.0 (93.8–100.0)

78.1

Specific interpretation

44.4 (0-93.1)

87.5 (78.8–96.2)

33.3 (0-79.5)

91.8 (84.6–99.0)

82.2

NI-RADS

66.7 (29.0-100.0)

87.5 (78.8–96.2)

42.9 (3.3–82.5)

94.9 (89.1–100.0)

84.9

SUVmax over 3.0

100.0 (66.7–100.0)

48.4 (30.8–66.0)

21.4 (0-48.2)

100.0 (90.3–100.0)

54.8

SUVmax over 4.0

100.0 (66.7–100.0)

71.9 (58.9–84.9)

33.3 (2.5–64.1)

100.0 (93.5–100.0)

75.4

Mass on primary tumor area

55.6 (12.1–99.2)

76.6 (64.8–88.5)

25.0 (0–63.0)

92.5 (85.1–99.9)

74.0

SUVmax over 4.0 and mass on primary tumor area

55.6 (12.1–99.2)

90.6 (83.1–98.1)

45.5 (1.9–89.1)

93.5 (87.2–99.8)

86.3

  1. In the sensitive interpretation, the equivocal result was interpreted as positive, and in the specific interpretation, the equivocal result was interpreted as negative