Table 1 Patient demographics, treatment results and pre-treatment imaging findings
From: PET-CT detection of local residual laryngeal carcinoma after definitive (chemo)radiotherapy
All patients, n = 73 | Residual or recurrent disease, n = 20 | No residual or recurrent disease, n = 53 | p-value | |
|---|---|---|---|---|
Gender, (%) | 0.329 | |||
Female | 15 (20.5) | 6 (30.0) | 9 (17.0) | |
Male | 58 (79.5) | 14 (70.0) | 44 (83.0) | |
T-stage, (%) | 0.128 | |||
T1 | 0 (0) | 0 (0) | 0 (0) | |
T2 | 28 (38.4) | 4 (20.0) | 24 (45.3) | |
T3 | 36 (49.3) | 13 (65.0) | 23 (43.4) | |
T4a | 8 (11.0) | 2 (10.0) | 6 (11.3) | |
T4b | 0 (0) | 0 (0) | 0 (0) | |
Missing | 1 (1.4) | 1 (5.0) | 0 (0) | |
N-stage, (%) | 0.111 | |||
N0 | 54 (74.0) | 17 (85.0) | 37 (69.8) | |
N1 | 7 (9.6) | 0 (0) | 7 (13.2) | |
N2a | 1 (1.4) | 1 (5.0) | 0 (0) | |
N2b | 4 (5.5) | 0 (0) | 4 (7.5) | |
N2c | 6 (8.2) | 1 (5.0) | 5 (9.4) | |
N3 | 0 (0) | 0 (0) | 0 (0) | |
Missing | 1 (1.4) | 1 (5.0) | 0 (0) | |
N-stage, (%) | 0.241 | |||
N0 | 54 (74.0) | 17 (85.0) | 37 (69.8) | |
N1-N2x | 19 (26.0) | 3 (15.0) | 16 (30.2) | |
Grade, (%) | 0.587 | |||
G1 | 9 (12.3) | 1 (5.0) | 8 (15.1) | |
G2 | 44 (60.3) | 13 (65.0) | 31 (58.5) | |
G3 | 12 (16.4) | 4 (20.0) | 8 (15.1) | |
Missing | 8 (11.0) | 2 (10.0) | 6 (11.3) | |
Smoking at diagnosis, (%) | 0.187 | |||
Yes | 50 (68.5) | 12 (60.0) | 38 (71.7) | |
Quit earlier | 16 (21.9) | 4 (20.0) | 12 (22.6) | |
Never | 7 (9.6) | 4 (20.0) | 3 (5.7) | |
Location of primary tumor according to the ICD code, (%) | 0.176 | |||
C32.0 Glottic | 29 (39.7) | 8 (40.0) | 21 (39.6) | |
C32.1 Supraglottic | 20 (27.4) | 4 (20.0) | 16 (30.2) | |
C32.2 Subglottic | 2 (2.7) | 2 (10.0) | 0 (0) | |
C32.8 Overlapping sites | 22 (30.1) | 6 (30.0) | 16 (30.2) | |
Treatment, (%) | 0.742 | |||
Chemoradiotherapy | 60 (82.2) | 16 (80.0) | 44 (83.0) | |
Radiotherapy only | 13 (17.8) | 4 (20.0) | 9 (17.0) | |
Cartilage erosion, (%) | 1.000 | |||
Yes | 28 (38.4) | 8 (40.0) | 20 (37.7) | |
No | 45 (61.6) | 12 (60.0) | 33 (62.3) | |
Paraglottic extension, (%) | 0.551 | |||
Yes | 55 (75.3) | 14 (70.0) | 41 (77.4) | |
No | 18 (24.7) | 6 (30.0) | 12 (22.6) | |
Died of laryngeal cancer, (%) | 0.012 | |||
Yes | 17 (23.3) | 9 (45.0) | 8 (15.1) | |
No | 56 (76.7) | 11 (55.0) | 45 (84.9) | |
Second primary, (%) | 0.763 | |||
Yes | 18 (24.7) | 4 (20.0) | 14 (26.4) | |
No | 55 (75.3) | 16 (80.0) | 39 (73.6) |