Fig. 3
From: PET-CT detection of local residual laryngeal carcinoma after definitive (chemo)radiotherapy
Possible false negative biopsy result after a positive PET-CT in a T3N0M0 disease. (a) At the 3-month post-treatment PET-CT, the patient presented with a left-sided, moderate focal vocal cord uptake (SUVmax 3.7) with expansion, left vocal cord paresis, opposite side arytenoid region uptake, and anterior neck muscle uptake. A biopsy of the vocal cord showed mild chronic inflammation and scar tissue, consistent with post-radiotherapy changes. The patient developed a strong supraglottic oedema, pain, and hoarseness. (b) In a repeat PET-CT 6 months later, the uptake area had progressed in size and intensity (SUVmax 7.0). The PET-CT revealed solitary lung metastasis (not shown). The residual tumor was surgically treated, but the patient later succumbed to the metastatic disease