Table 4 Correlation between IGFBPs CNV and IGFBPs expression
From: Expression characteristics and their functional role of IGFBP gene family in pan-cancer
Gene | Cancer type | CNV | n | Expression median value | P value |
|---|---|---|---|---|---|
IGFBP1 | BRCA | DEL | 19 | 0(0–1.585) | 0.045 |
GAIN | 34 | 2(1–2.896) |  | ||
No Change | 1037 | 1.585(0–2.585) |  | ||
OV | DEL | 18 | 2.5(1.146–3.387) | 0.045 | |
GAIN | 30 | 3.522(2.08–4.985) |  | ||
No Change | 329 | 3.459(2.322–4.807) |  | ||
IGFBP2 | BRCA | DEL | 48 | 11.881(10.332–12.928) | 0.003 |
GAIN | 35 | 12.49(11.017–13.376) |  | ||
No Change | 1007 | 12.726(11.625–13.491) |  | ||
CESC | DEL | 71 | 11.064(9.844–12.181) | < 0.001 | |
GAIN | 3 | 8.43(8.36–12.257) |  | ||
No Change | 220 | 12.548(10.626–13.705) |  | ||
OV | DEL | 55 | 14.78(14.242–15.876) | 0.011 | |
GAIN | 52 | 15.349(14.951–16.69) |  | ||
No Change | 270 | 15.583(14.609–16.21) |  | ||
PAAD | DEL | 3 | 10.011(9.76–11.867) | 0.016 | |
GAIN | 6 | 13.997(13.391–14.811) |  | ||
No Change | 168 | 12.227(11.325–13.006) |  | ||
PRAD | DEL | 9 | 12.611(12.287–12.931) | < 0.001 | |
GAIN | 5 | 13.896(12.477–14.945) |  | ||
No Change | 482 | 13.81(13.258–14.313) |  | ||
UCEC | DEL | 15 | 13.56(12.422–14.836) | 0.007 | |
GAIN | 9 | 15.199(15.088–15.404) |  | ||
No Change | 516 | 13.28(11.9–14.435) |  |