Expression characteristics and their functional role of IGFBP gene family in pan-cancer

BMC Cancer

Table 3 Correlation between IGFBPs expression and immune cell infiltration in Pan-cancer

Gene	Cancer Type	Cell Type	Correlation Coefficient	P value
IGFBP1	CHOL	T cells CD8	-0.46	0.007
IGFBP1	ACC	T cells CD4 memory resting	-0.44	0.004
IGFBP1	CHOL	Plasma cells	-0.42	0.015
IGFBP1	UCS	Neutrophils	0.41	0.009
IGFBP1	KICH	Dendritic cells activated	0.48	0.003
IGFBP2	UVM	Plasma cells	-0.64	< 0.001
IGFBP2	CHOL	NK cells activated	-0.53	0.002
IGFBP2	THYM	Mast cells resting	0.56	< 0.001
IGFBP2	MESO	Mast cells resting	-0.42	< 0.001
IGFBP2	KICH	Macrophages M2	0.44	0.008
IGFBP2	LGG	Macrophages M1	0.4	< 0.001
IGFBP2	KICH	Macrophages M0	0.51	0.002
IGFBP2	DLBC	Macrophages M0	0.46	0.001
IGFBP2	CHOL	B cells naive	0.4	0.021
IGFBP2	UVM	B cells naive	-0.43	0.012
IGFBP2	CHOL	B cells memory	-0.42	0.016
IGFBP3	TGCT	T cells CD4 memory activated	-0.45	< 0.001
IGFBP3	CHOL	NK cells activated	-0.48	0.005
IGFBP3	UCS	Neutrophils	0.51	< 0.001
IGFBP3	TGCT	Macrophages M2	0.67	< 0.001
IGFBP3	THYM	Macrophages M1	0.48	< 0.001
IGFBP3	ACC	B cells naive	-0.4	0.010
IGFBP3	TGCT	B cells naive	-0.65	< 0.001
IGFBP6	CHOL	T cells CD4 memory activated	0.4	0.023
IGFBP6	UVM	T cells CD4 memory activated	-0.4	0.020
IGFBP7	PCPG	Mast cells resting	0.4	< 0.001
IGFBP7	UCS	Macrophages M0	-0.4	0.012
IGFBP7	UVM	B cells naive	-0.4	0.020

ISSN: 1471-2407