Fig. 13
From: Expression characteristics and their functional role of IGFBP gene family in pan-cancer
Genetic alternations of IGFBPs in pan-cancer. A Mutation frequency of IGFBPs in different cancers. Red color represents high mutation frequency whereas blue color represents low mutation frequency. B Oncoplot for IGFBPs in UCEC. IGFBP5 shows the most frequent mutation in UCEC. C Mutation frequency of IGFBPs in different cancer cell lines (colorectal, gastric, liver, kidney, breast, lung, esophagus and ovary) from CCLE database. Red color represents high mutation frequency whereas blue color represents low mutation frequency. D The copy number variations frequency of IGFBPs in different cancers. The upper part of each grid shows the deletion frequency, and the bottom part shows the amplification frequency