Single-cell transcriptome analysis profiles the expression features of TMEM173 in BM cells of high-risk B-cell acute lymphoblastic leukemia

Table 1 Clinical features of 6 B-ALL patients and 3 healthy donors

Number	Sex	Age (years)	Diagnosis	Mutant genes	Diagnosis karyotypes	White blood cell counts (1 × 10^9/L)	Percentage of Naive cells in BM (%)	Stage
T1	Female	49	B-ALL	TP53, ZEB1, BCORL1, SPEN, KLF2, FAT1, FOXO3, KMT2C	47, XX, + 1 der(1;16)(q10;p10), + 8, t(9;22)(q34;q11.2) [3]	134.13	94	Diagnosis
T2	Male	15	B-ALL	ETV6, KRAS, EZH2	-	21.48	93	Diagnosis
T3	Male	67	Pre-B ALL	KRAS, NF1, PTEN, DNM2, TCF3, TP53	73 ~ 79 < 3n>,XXY, + 1, +4,+6, + 8, add(9)(p22); +16, + 17, -17, + 19, +21, + 22, inc [cp4]	5.69	99	Diagnosis
T4	Female	56	B-ALL (High-risk)	KRAS, NF1, PTEN, DNM2, TCF3, TP53	46,XX,t(2;12)(p13;p11),del(8)(p21) [6] /46,XX [4]	17.17	95	Diagnosis
T5	Male	46	Ph-positive B-ALL (High-risk)	BCR-ABL1	46, XY, t(9;22)( (q34;q11) [10]	52.69	90	Diagnosis
T6	Female	64	Ph-positive B-ALL (High-risk)	BCR-ABL1, SF1, USP7, SPIB, PLCG1, SF3A1, EP300, POT1, PTPRD	46, XX, t(9;22)( (q34;q11) [2]	57.35	96	Diagnosis
N1	Female	30
N2	Male	25
N3	Male	27

ISSN: 1471-2407