Fig. 3
From: SLC27A2 mediates FAO in colorectal cancer through nongenic crosstalk regulation of the PPARs pathway
SLC27A2 was associated with FAO metabolic genes in colorectal cancer. A ~ B SLC27A2 was overexpressed in HCT-15 and SW480 by plasmids and tested by qRT‒PCR. C ~ D The expression of FAO related genes were measured when SLC27A2 was overexpressed in CRC and the mRNA expression of CPT1A, SLC35G1, ACOX1, EHHADH, ABCD3, HADHA, HADHB, ETFA, and EPHX2 elevated in HCT-15 and SW480. E ~ F SLC27A2 was knocked down in HCT-15 and SW480 by siRNAs and verified using qRT‒PCR. G ~ H The mRNA expression levels of FAO–related genes were measured when SLC27A2 was knocked down in CRC and the mRNA expression of SLC25A20, ACOX1, ABCG2, ABCD3, HADHA, HADHB, HADH, and ETFA decreased in HCT-15 and SW480. NC: negative control; OE: over expression