Fig. 4

The proportion of cytotoxic T lymphocytes and concentration of granzyme B according to serum exoPD-L1 levels. No differences were observed between the two groups with respect to (A) total cytotoxic CD8 + T lymphocytes, (B) activated CD8 + T lymphocytes with CD69 expression, and (C) CD8 + T lymphocytes with PD-1 expression; however, (D) granzyme B concentration was higher in the high exoPD-L1 group