From: Intrathecal chemotherapy combined with systemic therapy in patients with refractory leptomeningeal metastasis of non-small cell lung cancer: a retrospective study
Clinical Manifestation
No. of patients (%)
Dizziness
27 (65.9%)
Headache
16 (39%)
Limb weakness
7 (17.1%)
Mental status changes
6 (14.6%)
Incontinence
2 (4.9%)
Epilepsy or convulsion
3 (4.6%)
Vision loss
Hearing loss
1 (2.4%)