Table 1 Characteristics of included studies for the meta-analyses
Reference | Year | Single-center/multicenter | Clinical study design | Country | Patient year | Patient | Tumor stage | Age(years) | Population | Neoadjuvant therapy | |
|---|---|---|---|---|---|---|---|---|---|---|---|
Number | Male/female | ||||||||||
Gu P [11] | 2021 | Multicenter | retrospective | China | 2001–2011 | 7620 | 5378/2242 | I-III | Median (range): 58.3 (15–89) | undergone curative gastric cancer resection with lymphadenectomy (R0 resection) | No |
Pan S [23] | 2019 | single-center | retrospective | China | 1987–2012 | 1730 | 1250/480 | I-III | Median (IQR): 58 (50–66) | underwent radical gastrectomy | Yes |
Cao H [24] | 2019 | single-center | retrospective | China | 2010–2012 | 877 | 605/272 | I-III | - | gastric adenocarcinoma R0 resection with D2 LN dissection | No |
Toth D [25] | 2017 | Multicenter | retrospective | Hungary | 2005–2010 | 164 | 99/65 | I-IV | Median (range): 66 (35–90) | gastric adenocarcinoma R0 resection | No |
Lee JW [34] | 2016 | single-center | retrospective | Korean | 1990–2012 | 3929 | 2623/1306 | NC | Median (range): 59 (18–91) | underwent curative (R0) resection and extended lymphadenectomy | UKN |
Jian-Hui C [35] | 2016 | single-center | retrospective | China | 1994–2008 | 935 | 636/299 | NC | mean (range): 57.5 (24–87) | gastric adenocarcinoma R0 resection with D2 LN dissection | No |
Spolverato G [15] | 2015 | Multicenter | retrospective | America | 2000–2012 | 804 | 468/336 | NC | Median (IQR): 66.1 (56.7–74.3) | underwent surgical resection of gastric adenocarcinoma | Yes |
Aurello P [36] | 2014 | single-center | retrospective | Italy | 1997–2012 | 177 | 107/70 | NC | mean (range): 65.9 (32–88) | gastric adenocarcinoma who underwent curative gastrectomy (R0) | No |
Xu J [12] | 2013 | single-center | retrospective | China | 2005–2008 | 427 | 281/146 | NC | - | underwent standard D2 radical gastrectomy | UKN |
Liu H [37] | 2013 | single-center | retrospective | China | 2001–2006 | 372 | 240/132 | NC | mean (range): 58.9 (20 − 79) | gastric adenocarcinoma R0 resection with D2 LN dissection and number of lymph nodes retrieved were no less than 15 | Yes |
Qiu MZ [38] | 2012 | single-center | retrospective | China | 1996–2006 | 730 | 522/208 | I-III | mean (range): 60 (24 − 83) | receiving D2 resection carried out by experienced surgeons in our hospital following the Japanese Gastric Cancer Association (JGCA) guidelines | UKN |
Sun Z [14] | 2010 | single-center | prospectively | China | 1980–2008 | 2547 | - | - | - | underwent D2 or D3 lymphadenectomy and achieved radical (R0) resection for histologically proven gastric carcinoma | UKN |